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In-Vivo ADME/DMPK Analysis

In Vivo Drug Metabolism and Pharmacokinetics

  1. Animal pharmacokinetics

  2. In-house SPF accredited animal facilities to house mice and rats.

  3. Studies with rabbits, guinea pigs, pigs, mini-pigs, and beagle dogs conducted with AAALAC accredited/GLP partner companies

  4. Single or multiple dosing

  5. Studies with small molecules, peptides,and proteins 

  6. Metabolite identification and profiling

  7. Bioanalysis by LC/MS/MS or UPLC/High-resolution-MS analysis

  8. UPLC with on-line radio detection

  9. Full pharmacokinetic evaluation using Phoenix® WinNonlin®