Nucleic acid therapeutics, based on nucleic acids or closely related chemical compounds, are an emerging new class of therapeutics for treating unmet medical needs. They are capable of targeting a disease at the genetic level by preventing the expression of disease-causing proteins.
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumour.
Tumor vaccines either treat existing cancer or prevent development of cancer. Tumor vaccines can develop from patient's immune cells or othe biological molecules.
A proteolysis targeting chimera is a heterobifunctional small molecule composed of two active domains and a linker, capable of removing specific unwanted proteins.
Antibody-drug conjugates (ADCs) are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells.